2350 Health Sciences Mall, Rm 2420 Life Sciences Institute, University of British Columbia Vancouver BC V6T 1Z3 Canada

News

Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity.

Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity.

Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity. Brigidi GS, Sun Y, Beccano-Kelly D, Pitman K, Mobasser M, Borgland SL, Milnerwood AJ, Bamji SX. (2014) Nature Neuroscience. Apr;17(4):522-32.PMID: 24562000

Hyperinsulinemia drives diet-induced obesity independently of brain insulin production.

Hyperinsulinemia drives diet-induced obesity independently of brain insulin production.

Hyperinsulinemia drives diet-induced obesity independently of brain insulin production. Mehran AE, Templeman NM, Brigidi GS, Lim GE, Chu KY, Hu X, Botezelli JD, Asadi A, Hoffman BG, Kieffer TJ, Bamji SX, Clee SM, Johnson JD. (2013) Cell Metabolism. Dec 5;16(6):723-37.PMID: 23217255Y.

Beta-pix modulates actin-mediated recruitment of synaptic vesicles to synapses.

Beta-pix modulates actin-mediated recruitment of synaptic vesicles to synapses.

Beta-pix modulates actin-mediated recruitment of synaptic vesicles to synapses. Y. Sun, S.X.Bamji (2011). Journal of Neuroscience. 31(47):17123-33.PMID: 22114281

Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses.

Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses.

Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses. L. Tapia, A. Milnerwood, A. Guo, F. Mills, E. Yoshida, C. Vasuta, I. Mackenzie, L. Raymond, M. Cynader, W. Jia and S.X. Bamji (2011). Journal of Neuroscience.31(31):11126-32.PMID: 21813674

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2 and b-catenin.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2 and b-catenin.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2 and b-catenin. Lee, S.-H., Peng, I-F., Ng, S., Yanagisawa, M., Bamji, S.X., Elia, L., Balsamo, J., Lilien, J., Anastasiadis, P.Z., Ullian, E. and Reichardt, L.F. (2008). Journal of Cell Biology. Dec 1;183(5):893-90.PMID: 19047464

BDNF mobilizes synaptic vesicles and regulates synaptic density via modulation of cadherin-b-catenin interactions.

BDNF mobilizes synaptic vesicles and regulates synaptic density via modulation of cadherin-b-catenin interactions.

BDNF mobilizes synaptic vesicles and regulates synaptic density via modulation of cadherin-b-catenin interactions. S.X. Bamji, B. Rico, N. Kimes, and L.F. Reichardt (2006). Journal of Cell Biology.174:289.PMID: 16831887