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Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2 and b-catenin.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2 and b-catenin.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2 and b-catenin. Lee, S.-H., Peng, I-F., Ng, S., Yanagisawa, M., Bamji, S.X., Elia, L., Balsamo, J., Lilien, J., Anastasiadis, P.Z., Ullian, E. and Reichardt, L.F. (2008). Journal of Cell Biology. Dec 1;183(5):893-90.PMID: 19047464

ErbB4-Neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms.

ErbB4-Neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms.

ErbB4-Neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms. Krivosheya D, Tapia L, Levinson JN, Huang K, Kang Y, Hines R, Ting AK, Craig AM, Mei L, Bamji S.X. * El-Husseini A*. (2008) Journal of Biological Chemistry. 283(47):32944.PMID: 18819924

BDNF mobilizes synaptic vesicles and regulates synaptic density via modulation of cadherin-b-catenin interactions.

BDNF mobilizes synaptic vesicles and regulates synaptic density via modulation of cadherin-b-catenin interactions.

BDNF mobilizes synaptic vesicles and regulates synaptic density via modulation of cadherin-b-catenin interactions. S.X. Bamji, B. Rico, N. Kimes, and L.F. Reichardt (2006). Journal of Cell Biology.174:289.PMID: 16831887

Cadherins: actin with the cytoskeleton to form synapses.

Cadherins: actin with the cytoskeleton to form synapses.

Cadherins: actin with the cytoskeleton to form synapses. S.X. Bamji (2005) Neuron. 47(2):175.PMID: 16039559

Role of b-catenin in synaptic vesicle localization and presynaptic assembly.

Role of b-catenin in synaptic vesicle localization and presynaptic assembly.

Role of b-catenin in synaptic vesicle localization and presynaptic assembly. S.X. Bamji, K. Shimazu, N. Kimes, J. Huelsken, W. Birchmeier, B. Lu and L.F. Reichardt. (2003). Neuron. 40(4):719-731.PMID: 14622577

P53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors.

P53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors.

P53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. R. Aloyz*,  S.X. Bamji*, C.D. Pozniak*, D.R. Kaplan, and F.D. Miller. (1998) Journal of Cell Biology. 143(6):1691-1703. (* Equal contributions by authors)PMID: 9852160

Autocrine hepatocyte growth factor provides a local mechanism for promoting axonal growth.

Autocrine hepatocyte growth factor provides a local mechanism for promoting axonal growth.

Autocrine hepatocyte growth factor provides a local mechanism for promoting axonal growth.  X.M. Yang, J. Toma, S.X. Bamji, J. Kohn, M. Park and F.D. Miller.  (1998) Journal of Neuroscience. 18:8369-8381.PMID: 9763480

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally-occurring sympathetic neuron death.

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally-occurring sympathetic neuron death.

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally-occurring sympathetic neuron death.  S.X. Bamji, M.Majdan, C.D. Pozniak, D.J. Belliveau, R. Aloyz, J.Kohn, C.G. Causing and F.D. Miller (1998) Journal of Cell Biology. 140(4):911-923.PMID: 9472042

Functional evidence that BDNF is an anterograde neuronal trophic factor in the central nervous system.

Functional evidence that BDNF is an anterograde neuronal trophic factor in the central nervous system.

Functional evidence that BDNF is an anterograde neuronal trophic factor in the central nervous system.  J. Fawcett*, S.X. Bamji*, R. Aloyz, C.G. Causing, T.A. Reader, D.R. Kaplan, R. Murphy, J. McLean and F.D. Miller.  (1998) Journal of Neuroscience. 18(8):2808-2821. (*Equal contributions by authors).PMID: 9525998

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis.

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis.

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis.  M. Majdan, C. Lachance, A. Gloster, R. Aloyz, C. Zeindler, S.X. Bamji, A. Bhakar, D.J. Belliveau, J.P. Fawcett, F.D. Miller, and P.A. Barker (1997) Journal of Neuroscience. 17(18):6988-6998.PMID: 9278534